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Allergy control, including saline nasal rinses and allergen avoidance where possible

Our transcriptomic results revealed that ECM1 knockdown in MenSCs was accompanied by the downregulation of genes that inhibit fibrosis, such as WNT2B and BMP4

But there are several obstacles to the development of this senolytic approach such as the long-term effect of CAR-T cells therapy with possible aspecific toxicity in different organs 56 , the cost and the difficulty during process development 57 or the selection of non-exhausted T cells to generate efficient therapy 58,59

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